The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid–Antipsychotic Drug Interactions

Cannabis use increases rates of psychotic relapse and treatment failure in schizophrenia patients. Clinical studies suggest that cannabis use reduces the efficacy of antipsychotic drugs, but there has been no direct demonstration of this in a controlled study. The present study demonstrates that exp...

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Detalhes bibliográficos
Publicado no:Neuropsychopharmacology
Main Authors: Brzozowska, Natalia I, de Tonnerre, Erik J, Li, Kong M, Wang, Xiao Suo, Boucher, Aurelie A, Callaghan, Paul D, Kuligowski, Michael, Wong, Alex, Arnold, Jonathon C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603813/
https://ncbi.nlm.nih.gov/pubmed/28272498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.50
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