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Palladium-catalyzed difluoromethylation of heteroaryl chlorides, bromides and iodides

A palladium-catalyzed difluoromethylation of a series of heteroaryl chlorides, bromides and iodides under mild conditions is described. A wide range of heteroaryl halides such as pyridyl, pyrimidyl, pyrazyl, funanyl, thienyl, pyazolyl, imidazolyl, thiazolyl, and oxazolyl halides were efficiently dif...

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Bibliographic Details
Published in:Chem Sci
Main Authors: Lu, Changhui, Gu, Yang, Wu, Jiang, Gu, Yucheng, Shen, Qilong
Format: Artigo
Language:Inglês
Published: Royal Society of Chemistry 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603793/
https://ncbi.nlm.nih.gov/pubmed/28959407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc00691h
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