HCN channels are a novel therapeutic target for cognitive dysfunction in Neurofibromatosis type 1

Cognitive impairments are a major clinical feature of the common neurogenetic disease neurofibromatosis type 1 (NF1). Previous studies have demonstrated that increased neuronal inhibition underlies the learning deficits in NF1, however, the molecular mechanism underlying this cell-type specificity h...

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Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Omrani, A, van der Vaart, T, Mientjes, E, van Woerden, GM, Hojjati, MR, Li, KW, Gutmann, DH, Levelt, CN, Smit, AB, Silva, AJ, Kushner, SA, Elgersma, Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603719/
https://ncbi.nlm.nih.gov/pubmed/25917366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2015.48
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