Single nucleotide polymorphisms of nucleotide excision repair pathway are significantly associated with outcomes of platinum-based chemotherapy in lung cancer

Nucleotide excision repair (NER) pathway plays critical roles in repairing DNA disorders caused by platinum. To comprehensively understand the association between variants of NER and clinical outcomes of platinum-based chemotherapy, 173 SNPs in 27 genes were selected to evaluate association with tox...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Sci Rep
Κύριοι συγγραφείς: Song, Xiao, Wang, Shiming, Hong, Xuan, Li, Xiaoying, Zhao, Xueying, Huai, Cong, Chen, Hongyan, Gao, Zhiqiang, Qian, Ji, Wang, Jiucun, Han, Baohui, Bai, Chunxue, Li, Qiang, Wu, Junjie, Lu, Daru
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Nature Publishing Group UK 2017
Θέματα:
Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603542/
https://ncbi.nlm.nih.gov/pubmed/28924235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08257-7
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