Genetic polymorphism of SLC31A1 is associated with clinical outcomes of platinum-based chemotherapy in non-small-cell lung cancer patients through modulating microRNA-mediated regulation

SLC31A1 is the major transporter for platinum drug intake, its expression correlates with drug disposition and response. In 1004 Chinese NSCLC patients with platinum-based chemotherapy, we investigated the association between SLC31A1 polymorphisms and clinical outcomes. Heterozygotes of rs10759637 a...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Chang, Zhang, Zhuojun, Qie, Jingbo, Wang, Yi, Qian, Ji, Wang, Jiucun, Wu, Junjie, Li, Qiang, Bai, Chunxue, Han, Baohui, Gao, Zhiqiang, Xu, Jibin, Lu, Daru, Jin, Li, Wang, Haijian
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5963629/
https://ncbi.nlm.nih.gov/pubmed/29844858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24794
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