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Population genomics of virulence genes of Plasmodium falciparum in clinical isolates from Uganda

Plasmodium falciparum causes a spectrum of malarial disease from asymptomatic to uncomplicated through to severe. Investigations of parasite virulence have associated the expression of distinct variants of the major surface antigen of the blood stages known as Pf EMP1 encoded by up to 60 var genes p...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ruybal-Pesántez, Shazia, Tiedje, Kathryn E., Tonkin-Hill, Gerry, Rask, Thomas S., Kamya, Moses R., Greenhouse, Bryan, Dorsey, Grant, Duffy, Michael F., Day, Karen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603532/
https://ncbi.nlm.nih.gov/pubmed/28924231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11814-9
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