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A Novel Mouse Model of Traumatic Optic Neuropathy Using External Ultrasound Energy to Achieve Focal, Indirect Optic Nerve Injury

Traumatic optic neuropathy (TON) is a devastating cause of permanent visual loss following blunt injury to the head. Animal models for TON exist, but most fail to recapitulate the clinical scenario of closed head indirect trauma to the nerve and subsequent neurodegeneration. Thus, we developed a cli...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Tao, Wensi, Dvoriantchikova, Galina, Tse, Brian C., Pappas, Steven, Chou, Tsung-Han, Tapia, Manuel, Porciatti, Vittorio, Ivanov, Dmitry, Tse, David T., Pelaez, Daniel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603527/
https://ncbi.nlm.nih.gov/pubmed/28924145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-12225-6
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