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Molecular mechanisms involved in the non-monotonic effect of bisphenol-a on Ca(2+) entry in mouse pancreatic β-cells

In regulatory toxicology, the dose-response relationship is a key element towards fulfilling safety assessments and satisfying regulatory authorities. Conventionally, the larger the dose, the greater the response, following the dogma “the dose makes the poison”. Many endocrine disrupting chemicals,...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Villar-Pazos, Sabrina, Martinez-Pinna, Juan, Castellano-Muñoz, Manuel, Alonso-Magdalena, Paloma, Marroqui, Laura, Quesada, Ivan, Gustafsson, Jan-Ake, Nadal, Angel
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603522/
https://ncbi.nlm.nih.gov/pubmed/28924161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11995-3
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