Genome-wide in vivo screen identifies novel host regulators of metastatic colonization

Metastasis is the leading cause of death for cancer patients. This multi-stage process requires tumour cells to survive in the circulation, extravasate at distant sites, then proliferate; it involves contributions from both the tumour cell and tumour microenvironment (‘host’, which includes stromal...

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Publicado no:Nature
Main Authors: van der Weyden, Louise, Arends, Mark J., Campbell, Andrew D., Bald, Tobias, Wardle-Jones, Hannah, Griggs, Nicola, Velasco-Herrera, Martin Del Castillo, Tüting, Thomas, Sansom, Owen J., Karp, Natasha A., Clare, Simon, Gleeson, Diane, Ryder, Edward, Galli, Antonella, Tuck, Elizabeth, Cambridge, Emma L., Voet, Thierry, Macaulay, Iain C., Wong, Kim, Spiegel, Sarah, Speak, Anneliese O., Adams, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603286/
https://ncbi.nlm.nih.gov/pubmed/28052056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature20792
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