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Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions

Proteins associated with neurodegenerative diseases are highly pleiomorphic and may adopt an all-α-helical fold in one environment, assemble into all-β-sheet or collapse into a coil in another, and rapidly polymerize in yet another one via divergent aggregation pathways that yield broad diversity of...

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Bibliografiske detaljer
Udgivet i:PLoS One
Hovedforfatter: Cieplak, Andrzej Stanisław
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603215/
https://ncbi.nlm.nih.gov/pubmed/28922400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180905
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