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Protein folding, misfolding and aggregation: The importance of two-electron stabilizing interactions

Proteins associated with neurodegenerative diseases are highly pleiomorphic and may adopt an all-α-helical fold in one environment, assemble into all-β-sheet or collapse into a coil in another, and rapidly polymerize in yet another one via divergent aggregation pathways that yield broad diversity of...

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Veröffentlicht in:PLoS One
1. Verfasser: Cieplak, Andrzej Stanisław
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603215/
https://ncbi.nlm.nih.gov/pubmed/28922400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180905
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