Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibod production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model

BACKGROUND: Recently, we have shown that an immunosuppression regimen including costimulation blockade via anti-CD154 antibody significantly prolongs the cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon heterotopic xenotransplantation model. Unfortunately, many coagulation disorders were o...

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Publicado en:Xenotransplantation
Main Authors: Mohiuddin, Muhammad M., Singh, Avneesh K., Corcoran, Philip C., Hoyt, Robert F., Thomas, Marvin L., Lewis, Billeta G. T., Eckhaus, Michael, Dabkowski, Nicole L., Belli, Aaron J., Reimann, Keith A., Ayares, David, Horvath, Keith A.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5603077/
https://ncbi.nlm.nih.gov/pubmed/24164510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/xen.12066
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