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Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases
The sigma-1 receptor (Sig-1R) is a chaperone that resides mainly at the mitochondrion-associated endoplasmic reticulum (ER) membrane (called the MAMs) and acts as a dynamic pluripotent modulator in living systems. At the MAM, the Sig-1R is known to play a role in regulating the Ca(2+) signaling betw...
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| Udgivet i: | J Biomed Sci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5603014/ https://ncbi.nlm.nih.gov/pubmed/28917260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-017-0380-6 |
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