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Sigma-1 receptor chaperones in neurodegenerative and psychiatric disorders

INTRODUCTION: Sigma-1 receptors (Sig-1Rs) are molecular chaperones that reside mainly in the endoplasmic reticulum (ER) but exist also in the proximity of the plasma membrane. Sig-1Rs are highly expressed in the CNS and are involved in many cellular processes including cell differentiation, neuritog...

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Detalhes bibliográficos
Publicado no:Expert Opin Ther Targets
Main Authors: Tsai, Shang-Yi A, Pokrass, Michael J, Klauer, Neal R, De Credico, Nicole E, Su, Tsung-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518923/
https://ncbi.nlm.nih.gov/pubmed/25331742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.972939
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