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Sigma-1 receptor chaperones in neurodegenerative and psychiatric disorders
INTRODUCTION: Sigma-1 receptors (Sig-1Rs) are molecular chaperones that reside mainly in the endoplasmic reticulum (ER) but exist also in the proximity of the plasma membrane. Sig-1Rs are highly expressed in the CNS and are involved in many cellular processes including cell differentiation, neuritog...
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Publicado no: | Expert Opin Ther Targets |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518923/ https://ncbi.nlm.nih.gov/pubmed/25331742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.972939 |
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