Cathepsin B as a potential cystatin M/E target in the mouse hair follicle

Deficiency of the cysteine protease inhibitor cystatin M/E (Cst6) in mice leads to disturbed epidermal cornification, impaired barrier function, and neonatal lethality. We report the rescue of the lethal skin phenotype of ichq (Cst6-deficient; Cst6(−/−)) mice by transgenic, epidermis-specific, reexp...

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Dades bibliogràfiques
Publicat a:FASEB J
Autors principals: Oortveld, Merel A. W., van Vlijmen-Willems, Ivonne M. J. J., Kersten, Ferry F. J., Cheng, Tsing, Verdoes, Martijn, van Erp, Piet E. J., Verbeek, Sjef, Reinheckel, Thomas, Hendriks, Wiljan J. A. J., Schalkwijk, Joost, Zeeuwen, Patrick L. J. M.
Format: Artigo
Idioma:Inglês
Publicat: Federation of American Societies for Experimental Biology 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602906/
https://ncbi.nlm.nih.gov/pubmed/28596234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700267R
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