Cathepsin B as a potential cystatin M/E target in the mouse hair follicle

Deficiency of the cysteine protease inhibitor cystatin M/E (Cst6) in mice leads to disturbed epidermal cornification, impaired barrier function, and neonatal lethality. We report the rescue of the lethal skin phenotype of ichq (Cst6-deficient; Cst6(−/−)) mice by transgenic, epidermis-specific, reexp...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Oortveld, Merel A. W., van Vlijmen-Willems, Ivonne M. J. J., Kersten, Ferry F. J., Cheng, Tsing, Verdoes, Martijn, van Erp, Piet E. J., Verbeek, Sjef, Reinheckel, Thomas, Hendriks, Wiljan J. A. J., Schalkwijk, Joost, Zeeuwen, Patrick L. J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602906/
https://ncbi.nlm.nih.gov/pubmed/28596234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201700267R
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