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Epigenetic clocks for gestational age: statistical and study design considerations

In this letter to the editor, we highlight some concerns with a recently published method to estimate gestational age at delivery from DNA methylation data. We conduct novel analyses to highlight the implications of different choices in study design and statistical methods for the prediction of phen...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Simpkin, Andrew J., Suderman, Matthew, Howe, Laura D.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602851/
https://ncbi.nlm.nih.gov/pubmed/28932320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-017-0402-y
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