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Nitric oxide prevents Aft1 activation and metabolic remodeling in frataxin-deficient yeast
Yeast frataxin homolog (Yfh1) is the orthologue of human frataxin, a mitochondrial protein whose deficiency causes Friedreich Ataxia. Yfh1 deficiency activates Aft1, a transcription factor governing iron homeostasis in yeast cells. Although the mechanisms causing this activation are not completely u...
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| 出版年: | Redox Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Elsevier
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5602528/ https://ncbi.nlm.nih.gov/pubmed/28918000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.09.001 |
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