Engineered outer membrane vesicle is potent to elicit HPV16E7-specific cellular immunity in a mouse model of TC-1 graft tumor

PURPOSE: Currently, therapeutic tumor vaccines under development generally lack significant effects in human clinical trials. Exploring a powerful antigen delivery system is a potential approach to improve vaccine efficacy. We sought to explore engineered bacterial outer membrane vesicles (OMVs) as...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Wang, Shijie, Huang, Weiwei, Li, Kui, Yao, Yufeng, Yang, Xu, Bai, Hongmei, Sun, Wenjia, Liu, Cunbao, Ma, Yanbing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602458/
https://ncbi.nlm.nih.gov/pubmed/28979120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S143264
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