Chimeric HBcAg virus-like particles presenting a HPV 16 E7 epitope significantly suppressed tumor progression through preventive or therapeutic immunization in a TC-1-grafted mouse model

BACKGROUND: Therapeutic human papillomavirus (HPV) vaccines are currently being developed. However, no therapeutic efficacy has been achieved in clinical trials for the treatment of cervical intraepithelial neoplasia or cancer. One of the important issues in increasing vaccine efficacy is determinin...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Chu, Xiaojie, Li, Yang, Long, Qiong, Xia, Ye, Yao, Yufeng, Sun, Wenjia, Huang, Weiwei, Yang, Xu, Liu, Cunbao, Ma, Yanbing
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892837/
https://ncbi.nlm.nih.gov/pubmed/27313455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S102467
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