Carbon Nanoparticles Inhibit the Antimicrobial Activities of the Human Cathelicidin LL-37 through Structural Alteration

Host defense peptides, also known as antimicrobial peptides, are key elements of innate host defense. One host defense peptide with well-characterized antimicrobial activity is the human cathelicidin, LL-37. LL-37 has been shown to be upregulated at sites of infection and inflammation and is regarde...

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Bibliographic Details
Published in:J Immunol
Main Authors: Findlay, Fern, Pohl, Jan, Svoboda, Pavel, Shakamuri, Priyanka, McLean, Kevin, Inglis, Neil F., Proudfoot, Lorna, Barlow, Peter G.
Format: Artigo
Language:Inglês
Published: AAI 2017
Subjects:
Innate Immunity and Inflammation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602159/
https://ncbi.nlm.nih.gov/pubmed/28814602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1700706
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