Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.

In age-related macular degeneration (AMD) the retinal pigment epithelium (RPE) deteriorates, leading to photoreceptor decay and severe vision loss. New therapeutic strategies aim at RPE replacement by transplantation of pluripotent stem cell (PSC)-derived RPE. Several protocols to generate RPE have...

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Gepubliceerd in:Stem Cell Rev
Hoofdauteurs: Bennis, A., Jacobs, J. G., Catsburg, L. A. E., ten Brink, J. B., Koster, C., Schlingemann, R. O., van Meurs, J., Gorgels, T. G. M. F., Moerland, P. D., Heine, V. M., Bergen, A. A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer US 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602068/
https://ncbi.nlm.nih.gov/pubmed/28730556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9754-0
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