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Stem Cell Derived Retinal Pigment Epithelium: The Role of Pigmentation as Maturation Marker and Gene Expression Profile Comparison with Human Endogenous Retinal Pigment Epithelium.

In age-related macular degeneration (AMD) the retinal pigment epithelium (RPE) deteriorates, leading to photoreceptor decay and severe vision loss. New therapeutic strategies aim at RPE replacement by transplantation of pluripotent stem cell (PSC)-derived RPE. Several protocols to generate RPE have...

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Detalhes bibliográficos
Publicado no:Stem Cell Rev
Main Authors: Bennis, A., Jacobs, J. G., Catsburg, L. A. E., ten Brink, J. B., Koster, C., Schlingemann, R. O., van Meurs, J., Gorgels, T. G. M. F., Moerland, P. D., Heine, V. M., Bergen, A. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602068/
https://ncbi.nlm.nih.gov/pubmed/28730556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-017-9754-0
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