Comparison of Mouse and Human Retinal Pigment Epithelium Gene Expression Profiles: Potential Implications for Age-Related Macular Degeneration

BACKGROUND: The human retinal pigment epithelium (RPE) plays an important role in the pathogenesis of age related macular degeneration (AMD). AMD is the leading cause of blindness worldwide. There is currently no effective treatment available. Preclinical studies in AMD mouse models are essential to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Bennis, Anna, Gorgels, Theo G. M. F., ten Brink, Jacoline B., van der Spek, Peter J., Bossers, Koen, Heine, Vivi M., Bergen, Arthur A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4627757/
https://ncbi.nlm.nih.gov/pubmed/26517551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141597
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