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Change from lung adenocarcinoma to small cell lung cancer as a mechanism of resistance to afatinib
We report the case of a patient affected by advanced EGFR mutation-positive lung who experienced resistance to therapy during treatment with Afatinib through the occurrence of a switch of tumor histotype to small cell lung cancer (SCLC) with features of a G3 neuroendocrine carcinoma. Unexpectedly, t...
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| Publicat a: | Oncotarget |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Impact Journals LLC
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601795/ https://ncbi.nlm.nih.gov/pubmed/28938699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17607 |
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