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Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma
The role of the positive RNA Pol II regulator, P-TEFb (positive transcription elongation factor b), in maintenance of the anti-apoptotic protein Mcl-1 and bortezomib (btz) resistance was investigated in human multiple myeloma (MM) cells. Mcl-1 was up-regulated in all MM lines tested, including borte...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5601747/ https://ncbi.nlm.nih.gov/pubmed/28938651 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19761 |
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