Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading

OBJECTIVE: Short-term neurectomy-induced disuse (SN) has been shown to restore load responses in aged mice. We examined whether this restoration was further enhanced in both cortical and trabecular bone by simply extending the SN. METHODS: Following load: strain calibration, tibiae in female C57BL/J...

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Pubblicato in:J Musculoskelet Neuronal Interact
Autori principali: Souza, R. De, Javaheri, B., Collinson, R.S., Chenu, C., Shefelbine, S.J., Lee, P.D., Pitsillides, A.A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: International Society of Musculoskeletal and Neuronal Interactions 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601267/
https://ncbi.nlm.nih.gov/pubmed/28860424
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