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Transient peak-strain matching partially recovers the age-impaired mechanoadaptive cortical bone response

Mechanoadaptation maintains bone mass and architecture; its failure underlies age-related decline in bone strength. It is unclear whether this is due to failure of osteocytes to sense strain, osteoblasts to form bone or insufficient mechanical stimulus. Mechanoadaptation can be restored to aged bone...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Javaheri, Behzad, Carriero, Alessandra, Wood, Maria, De Souza, Roberto, Lee, Peter D., Shefelbine, Sandra, Pitsillides, Andrew A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5924380/
https://ncbi.nlm.nih.gov/pubmed/29703931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-25084-6
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