Divergent Synthesis of Cyclopropane‐Containing Lead‐Like Compounds, Fragments and Building Blocks through a Cobalt Catalyzed Cyclopropanation of Phenyl Vinyl Sulfide

Cyclopropanes provide important design elements in medicinal chemistry and are widely present in drug compounds. Here we describe a strategy and extensive synthetic studies for the preparation of a diverse collection of cyclopropane‐containing lead‐like compounds, fragments and building blocks explo...

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Veröffentlicht in:European J Org Chem
Hauptverfasser: Chawner, Stephen J., Cases‐Thomas, Manuel J., Bull, James A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601191/
https://ncbi.nlm.nih.gov/pubmed/28983191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201701030
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