NOTCH1 activates the Wnt/β-catenin signaling pathway in colon cancer

PURPOSE AND METHODS: The translocation of β-catenin/CTNNB1 to the nucleus activates Wnt signaling and cell proliferation; however, the precise mechanism underlying this phenomenon remains unknown. Previous reports have provided evidence that NOTCH1 is involved in the Wnt signaling pathway. Therefore...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Ishiguro, Hideyuki, Okubo, Tomotaka, Kuwabara, Yoshiyuki, Kimura, Masahiro, Mitsui, Akira, Sugito, Nobuyoshi, Ogawa, Ryo, Katada, Takeyasu, Tanaka, Tatsuya, Shiozaki, Midori, Mizoguchi, Koji, Samoto, Yosuke, Matsuo, Yoichi, Takahashi, Hiroki, Takiguchi, Shuji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601146/
https://ncbi.nlm.nih.gov/pubmed/28947978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19534
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