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Decreased expression of FBXW7 is correlated with poor prognosis in patients with esophageal squamous cell carcinoma

FBXW7 is a tumor suppressor gene that induces the degradation of positive cell-cycle regulators such as c-Myc, cyclin E, c-Jun and Notch. The loss of FBXW7 promotes cell-cycle progression and cell proliferation. In the present study, we investigated the relationship between FBXW7 expression and the...

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Detalhes bibliográficos
Main Authors: NAGANAWA, YASUHIRO, ISHIGURO, HIDEYUKI, KUWABARA, YOSHIYUKI, KIMURA, MASAHIRO, MITSUI, AKIRA, KATADA, TAKEYASU, TANAKA, TATSUYA, SHIOZAKI, MIDORI, FUJII, YOSHITAKA, TAKEYAMA, HIROMITSU
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445893/
https://ncbi.nlm.nih.gov/pubmed/22993608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2010.115
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