TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics

Neuroinflammation is a hallmark of Alzheimer's disease and TNFα as the main inducer of neuroinflammation has neurodegenerative but also pro-regenerative properties, however, the dose-dependent molecular changes on signaling pathway level are not fully understood. We performed quantitative prote...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jensen, Pia, Myhre, Christa L., Lassen, Pernille S., Metaxas, Athanasios, Khan, Asif M., Lambertsen, Kate L., Babcock, Alicia A., Finsen, Bente, Larsen, Martin R., Kempf, Stefan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601134/
https://ncbi.nlm.nih.gov/pubmed/28947966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.19428
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