Quantitative Phospho-proteomics to Investigate the Polo-like Kinase 1-Dependent Phospho-proteome

Polo-like kinase 1 (PLK1) is a key regulator of mitotic progression and cell division, and small molecule inhibitors of PLK1 are undergoing clinical trials to evaluate their utility in cancer therapy. Despite this importance, current knowledge about the identity of PLK1 substrates is limited. Here w...

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Hlavní autoři: Grosstessner-Hain, Karin, Hegemann, Björn, Novatchkova, Maria, Rameseder, Jonathan, Joughin, Brian A., Hudecz, Otto, Roitinger, Elisabeth, Pichler, Peter, Kraut, Norbert, Yaffe, Michael B., Peters, Jan-Michael, Mechtler, Karl
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Biochemistry and Molecular Biology 2011
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3226402/
https://ncbi.nlm.nih.gov/pubmed/21857030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M111.008540
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