Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells

Using high-throughput small molecule screening targeting furin gene, we identified that phorbol esters dPPA (12-Deoxyphorbol 13-phenylacetate 20-acetate) and dPA (12-Deoxyphorbol 13-acetate) significantly increased furin protein and mRNA expression in SH-SY5Y cells. This effect was prevented by PKC...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zha, Jing-Si, Zhu, Bing-Lin, Liu, Lu, Lai, Yu-Jie, Long, Yan, Hu, Xiao-Tong, Deng, Xiao-Juan, Wang, Xue-Feng, Yan, Zhen, Chen, Guo-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601129/
https://ncbi.nlm.nih.gov/pubmed/28947961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18569
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