Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells

ERBB2 receptor belongs to the ERBB tyrosine kinase receptor family. At variance to the other family members, ERBB2 is a constitutively active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo- or hetero-dimers with the other family members, including ERBB2, promoting an i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Bagnato, Paola, Castagnino, Alessia, Cortese, Katia, Bono, Maria, Grasso, Silvia, Bellese, Grazia, Daniele, Tiziana, Lundmark, Richard, Defilippi, Paola, Castagnola, Patrizio, Tacchetti, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601125/
https://ncbi.nlm.nih.gov/pubmed/28947957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17686
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