Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells

ERBB2 receptor belongs to the ERBB tyrosine kinase receptor family. At variance to the other family members, ERBB2 is a constitutively active orphan receptor. Upon ligand binding and activation, ERBB receptors form homo- or hetero-dimers with the other family members, including ERBB2, promoting an i...

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書目詳細資料
發表在:Oncotarget
Main Authors: Bagnato, Paola, Castagnino, Alessia, Cortese, Katia, Bono, Maria, Grasso, Silvia, Bellese, Grazia, Daniele, Tiziana, Lundmark, Richard, Defilippi, Paola, Castagnola, Patrizio, Tacchetti, Carlo
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5601125/
https://ncbi.nlm.nih.gov/pubmed/28947957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17686
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