The chromodomain helicase CHD4 regulates ERBB2 signaling pathway and autophagy in ERBB2(+) breast cancer cells

The chromodomain helicase DNA-binding 4 (CHD4), a member of the nucleosome remodeling and deacetylases (NuRD) complex, has been identified as an oncogene that modulates proliferation and migration of breast cancers (BC). ERBB2 is an oncogenic driver in 20–30% of BC in which its overexpression leads...

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Publicat a:Biol Open
Autors principals: D'Alesio, Carolina, Bellese, Grazia, Gagliani, Maria Cristina, Lechiara, Anastasia, Dameri, Martina, Grasselli, Elena, Lanfrancone, Luisa, Cortese, Katia, Castagnola, Patrizio
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504000/
https://ncbi.nlm.nih.gov/pubmed/30967373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.038323
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