AR-13, a Celecoxib Derivative, Directly Kills Francisella In Vitro and Aids Clearance and Mouse Survival In Vivo

Francisella tularensis (F. tularensis) is the causative agent of tularemia and is classified as a Tier 1 select agent. No licensed vaccine is currently available in the United States and treatment of tularemia is confined to few antibiotics. In this study, we demonstrate that AR-13, a derivative of...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Hoang, Ky V., Adcox, Haley E., Fitch, James R., Gordon, David M., Curry, Heather M., Schlesinger, Larry S., White, Peter, Gunn, John S.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600997/
https://ncbi.nlm.nih.gov/pubmed/28955308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2017.01695
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