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In Vitro and In Vivo Biocompatibility Evaluation of Polyallylamine and Macromolecular Heparin Conjugates Modified Alginate Microbeads

Host reactivity to biocompatible immunoisolation devices is a major challenge for cellular therapies, and a human screening model would be of great value. We designed new types of surface modified barium alginate microspheres, and evaluated their inflammatory properties using human whole blood, and...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vaithilingam, Vijayaganapathy, Steinkjer, Bjørg, Ryan, Liv, Larsson, Rolf, Tuch, Bernard Edward, Oberholzer, Jose, Rokstad, Anne Mari
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600981/
https://ncbi.nlm.nih.gov/pubmed/28916826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11989-1
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