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Internalization, axonal transport and release of fibrillar forms of alphasynuclein

Intra-neuronal protein aggregates made of fibrillar alpha-synuclein (α-syn) are the hallmark of Parkinson’s disease (PD). With time, these aggregates spread through the brain following axonal projections. Understanding the mechanism of this spread is central to the study of the progressive nature of...

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Dettagli Bibliografici
Pubblicato in:Neurobiol Dis
Autori principali: Bieri, Gregor, Gitler, Aaron D., Brahic, Michel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600643/
https://ncbi.nlm.nih.gov/pubmed/28323023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.03.007
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