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Internalization, axonal transport and release of fibrillar forms of alphasynuclein

Intra-neuronal protein aggregates made of fibrillar alpha-synuclein (α-syn) are the hallmark of Parkinson’s disease (PD). With time, these aggregates spread through the brain following axonal projections. Understanding the mechanism of this spread is central to the study of the progressive nature of...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Bieri, Gregor, Gitler, Aaron D., Brahic, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600643/
https://ncbi.nlm.nih.gov/pubmed/28323023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.03.007
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