CD44 induced enhancement of phosphatase activity and calcium influx: Modifications of EGR-1 expression and cell proliferation

The purpose of this study was to investigate how CD44 impaired Akt phosphorylation, EGR-1 expression and cell proliferation. E6.1 Jurkat cells, which lack endogenous CD44 expression, were engineered to express CD44. Previously we showed that Akt is hypophosphorylated, EGR-1 expression is reduced and...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Racine, Ronny R., Manalo, Nathan A., Hall, Jessica M.F., Dibas, Adnan, Raffel, Glen D., Mummert, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600419/
https://ncbi.nlm.nih.gov/pubmed/28955875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2016.03.016
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