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tPA and anger management for macrophages
In this issue of Blood, Mantuano et al in the Gonias laboratory elucidate a novel, protease-independent signaling pathway by which tissue plasminogen activator (tPA) negatively regulates the innate immune response of macrophages and neutralizes lipopolysaccharide (LPS) toxicity in vivo.(1)
Guardat en:
| Publicat a: | Blood |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society of Hematology
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5600143/ https://ncbi.nlm.nih.gov/pubmed/28912293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-795906 |
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