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tPA and anger management for macrophages

In this issue of Blood, Mantuano et al in the Gonias laboratory elucidate a novel, protease-independent signaling pathway by which tissue plasminogen activator (tPA) negatively regulates the innate immune response of macrophages and neutralizes lipopolysaccharide (LPS) toxicity in vivo.(1)

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Bibliografske podrobnosti
izdano v:Blood
Main Authors: Miles, Lindsey A., Parmer, Robert J.
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5600143/
https://ncbi.nlm.nih.gov/pubmed/28912293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-795906
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