Cholesterol 25-Hydroxylase Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication through Enzyme Activity-Dependent and -Independent Mechanisms

Cholesterol 25-hydroxylase (CH25H) has recently been identified as a host restriction factor that exerts antiviral effects by catalyzing the production of 25-hydroxycholesterol (25HC). CH25H can be rapidly induced upon infection with some viruses. Porcine reproductive and respiratory syndrome virus...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Ke, Wenting, Fang, Liurong, Jing, Huiyuan, Tao, Ran, Wang, Ting, Li, Yang, Long, Siwen, Wang, Dang, Xiao, Shaobo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Virus-Cell Interactions
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599739/
https://ncbi.nlm.nih.gov/pubmed/28724759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00827-17
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