Porcine Reproductive and Respiratory Syndrome Virus nsp1α Inhibits NF-κB Activation by Targeting the Linear Ubiquitin Chain Assembly Complex

Linear ubiquitination, a newly discovered posttranslational modification, is catalyzed by the linear ubiquitin chain assembly complex (LUBAC), which is composed of three subunits: one catalytic subunit HOIP and two accessory molecules, HOIL-1L and SHARPIN. Accumulating evidence suggests that linear...

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Veröffentlicht in:J Virol
Hauptverfasser: Jing, Huiyuan, Fang, Liurong, Ding, Zhen, Wang, Dang, Hao, Wenqi, Gao, Li, Ke, Wenting, Chen, Huanchun, Xiao, Shaobo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244335/
https://ncbi.nlm.nih.gov/pubmed/27881655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01911-16
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