DNA methylation profiling reveals common signatures of tumorigenesis and defines epigenetic prognostic subtypes of canine Diffuse Large B-cell Lymphoma

Epigenetic deregulation is a hallmark of cancer characterized by frequent acquisition of new DNA methylation in CpG islands. To gain insight into the methylation changes of canine DLBCL, we investigated the DNA methylome in primary DLBCLs in comparison with control lymph nodes by genome-wide CpG mic...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ferraresso, Serena, Aricò, Arianna, Sanavia, Tiziana, Da Ros, Silvia, Milan, Massimo, Cascione, Luciano, Comazzi, Stefano, Martini, Valeria, Giantin, Mery, Di Camillo, Barbara, Mazzariol, Sandro, Giannuzzi, Diana, Marconato, Laura, Aresu, Luca
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599585/
https://ncbi.nlm.nih.gov/pubmed/28912427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-11724-w
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