Calcium/calmodulin‐dependent kinase 2 mediates Epac‐induced spontaneous transient outward currents in rat vascular smooth muscle

KEY POINTS: The Ca(2+) and redox‐sensing enzyme Ca(2+)/calmodulin‐dependent kinase 2 (CaMKII) is a crucial and well‐established signalling molecule in the heart and brain. In vascular smooth muscle, which controls blood flow by contracting and relaxing in response to complex Ca(2+) signals and oxida...

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Vydáno v:J Physiol
Hlavní autoři: Humphries, Edward S. A., Kamishima, Tomoko, Quayle, John M., Dart, Caroline
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Cardiovascular
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599484/
https://ncbi.nlm.nih.gov/pubmed/28731505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274754
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