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Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine
Asparagine is conserved in the S6 transmembrane segments of all voltage-gated sodium, calcium, and TRP channels identified to date. A broad spectrum of channelopathies including cardiac arrhythmias, epilepsy, muscle diseases, and pain disorders is associated with its mutation. To investigate its eff...
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Yayımlandı: | Eur Biophys J |
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Asıl Yazarlar: | , , , , , , |
Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Springer International Publishing
2017
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599482/ https://ncbi.nlm.nih.gov/pubmed/28825121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-017-1246-2 |
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