Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine

Asparagine is conserved in the S6 transmembrane segments of all voltage-gated sodium, calcium, and TRP channels identified to date. A broad spectrum of channelopathies including cardiac arrhythmias, epilepsy, muscle diseases, and pain disorders is associated with its mutation. To investigate its eff...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Eur Biophys J
Prif Awduron: O’Reilly, Andrias O., Lattrell, Anja, Miles, Andrew J., Klinger, Alexandra B., Nau, Carla, Wallace, B. A., Lampert, Angelika
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer International Publishing 2017
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599482/
https://ncbi.nlm.nih.gov/pubmed/28825121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00249-017-1246-2
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