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Increased Pre-Transplant Frequency of CD28(+) CD4(+) T(EM) Predicts Belatacept-Resistant Rejection in Human Renal Transplant Recipients

While most human T cells express the CD28 costimulatory molecule constitutively, it is well-known that age, inflammation, and viral infection can drive the generation of CD28(null) T cells. In vitro studies have demonstrated that CD28(null) cell effector function is not impacted by the presence of t...

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Detalhes bibliográficos
Publicado no:Am J Transplant
Main Authors: Cortes-Cerisuelo, Miriam, Laurie, Sonia J., Mathews, David V., Winterberg, Pamela D., Larsen, Christian P., Adams, Andrew B., Ford, Mandy L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5599135/
https://ncbi.nlm.nih.gov/pubmed/28502091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ajt.14350
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