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Chemically Controlled Epigenome Editing Through an Inducible dCas9 System
Although histone modifications are associated with gene activities, studies of their causal relationships have been difficult. For this purpose, we developed an inducible system integrating dCas9-based targeting and chemically induced proximity technologies to allow small molecule induced recruitmen...
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| Publicat a: | J Am Chem Soc |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5599110/ https://ncbi.nlm.nih.gov/pubmed/28787145 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b06555 |
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