Src- and Fyn-dependent apical membrane trafficking events control endothelial lumen formation during vascular tube morphogenesis

Here we examine the question of how endothelial cells (ECs) develop their apical membrane surface domain during lumen and tube formation. We demonstrate marked apical membrane targeting of activated Src kinases to this apical domain during early and late stages of this process. Immunostaining for ph...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kim, Dae Joong, Norden, Pieter R., Salvador, Jocelynda, Barry, David M., Bowers, Stephanie L. K., Cleaver, Ondine, Davis, George E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598984/
https://ncbi.nlm.nih.gov/pubmed/28910325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184461
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